One of the most important metabolic links between neurons and astrocytes, however, is the glutamate–glutamine shuttle. Astrocytes transport the vast majority of extracellular glutamate ...

Astrocytes from both groups had deficits in glutamate signaling. The cool part is what happened next: When they exposed astrocytes to clozapine, glutamate signaling normalized—but only in the ...

Astrocytes connect and support communication ... NO synthesis is self-sustaining, supported by the NO-glutamate loop, but blocking molecular steps for NO-synthesis or those that trigger glutamate ...

This review considers the role that optic nerve head astrocytes might play in the initiation of axon damage, based on the hypothesis that these cells are sensitive to mechanical or ischaemic ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

Some examples of mouse models in which astrocyte protein function is altered are detailed in Table 1. In addition to cellular hypertrophy and upregulation of specific genes associated with ...