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A high-resolution 'map' reveals the structural and functional complexity of endogenous NMDA receptors in the brainhas dissected the assembly and architecture of endogenous N-methyl-ᴅ-aspartate receptors (eNMDARs) in the adult mammalian cerebral cortex and hippocampus. Learning and memory are fundamental ...
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FDA grants breakthrough status to Grin Therapeutics’ radiprodilThe US Food and Drug Administration (FDA) has granted breakthrough therapy designation to Grin Therapeutics’ radiprodil for treating seizures associated with glutamate receptor, ionotropic, N-methyl D ...
The following is a summary of "Unveiling the oncogenic role of SLC25A13: a multi-omics pan-cancer analysis reveals its impact ...
L’acide aspartique (dont l'anion s'appelle aspartate) est l'un des 20 acides-α-aminés constituant les protéines. Il s'agit de l'acide carboxylique proche de l'asparagine. C'est un acide dicarboxylique ...
The FDA has granted Breakthrough Therapy designation to radiprodil for the treatment of seizures associated with GRIN-related neurodevelopmental disorder with GoF mutations.
Neurodevelopmental disorders company GRIN Therapeutics, an affiliate of the Blackstone Life Sciences portfolio company Neurvati Neurosciences, has announced a major milestone.
Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and a leading monogenic cause of autism, yet effective treatments remain elusive. Previous work showed that ...
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