Not all antigens insert themselves into a cell membrane ... Thus, a division of labor may emerge in intact antigen presentation. DC subsets may present antigen to naïve B cells, whereas the ...

Tolerogenic dendritic cells in the intestines are shown to reduce the immune responses caused by exposure to food proteins.

Antigen presentation by major histocompatibility complex (MHC) proteins is the caller ID of the immune system. On the cell surface, MHCs display peptides derived from cellular components or foreign ...

The CAR T-cell therapy KYV-101 is safe, and showed preliminary signs of efficacy in patients with progressive forms of MS in ...

TCEs work by simultaneously binding to a tumor-associated antigen ... Unlike traditional T cell responses, TCEs do not ...

CD3 T-cell engagers have the potential to be a cornerstone of cancer treatment. They guide the immune system to find and eliminate cancer cells by binding tumor targets and the CD3 protein on ...

To date, the Food and Drug Administration (FDA) has approved seven chimeric antigen receptor-T (CAR-T) cell therapies and seven bispecific T-cell engagers (BiTEs) across a variety of hematologic ...

C.A. Details of the poster presentation are as follows: Abstract Title: ADI-270, an Armored Allogeneic Anti-CD70 γδ CAR T Cell Therapy, Demonstrates Improved Efficacy and Safety in Preclinical ...