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Mandimycin, which targets a different essential fungi cell resource than other antifungal drugs, should harm other cell types as collateral — but doesn’t.
To combat long-overlooked fungal pathogens, researchers and regulators must embrace innovative science and policy.
Writing in Nature, Deng et al. report the discovery of a novel polyene antifungal, mandimycin, that exhibits a unique mode of action. Mandimycin demonstrated potent and broad-spectrum fungicidal ...
“Not only is the pipeline of new antifungal drugs and diagnostics insufficient, there is a void in fungal testing in low- and middle-income countries, even in district hospitals. This diagnostic ...
The World Health Organization (WHO) today published its first-ever reports addressing the critical lack of medicines and ...
As with antibiotics, controlling the use of fungicides in agriculture is seen as key to fending off the rising threat of antimicrobial resistance - iStockphoto ...
Not only is the pipeline of new antifungal drugs and diagnostics insufficient, there is a void in fungal testing in low- and middle-income countries, even in district hospitals. This diagnostic ...
Cinnamon is one of the oldest and most commonly used spices in the world, but a new study from the National Center for ...
He also pointed to growing concern over agricultural antifungal use. “A lot of the new drugs being developed don’t have a novel mechanism of action,” Beardsley said. And in many cases ...
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