The WHO’s new reports on invasive fungal infections highlight the urgent need for global action to address the critical shortages in antifungal treatments and diagnostics.

The World Health Organization (WHO) has raised alarms over the increasing threat posed by drug-resistant fungal infections, calling it a growing global health concern. In its first-ever report on ...

For example, antifungal agents are often classified into three groups, depending on their site of action: the polyenes interact with fungal membrane–building blocks; azoles inhibit the synthesis ...

Mandimycin is structurally similar to the last-line-of-defense antifungal amphotericin B, another glycosylated polyene macrolide. But instead of binding to ergosterol in the fungal cell membrane as ...

The World Health Organization warns of increasing resistance to treatments for fungal diseases, especially among vulnerable ...

Antifungal agents are substances that inhibit the spread of fungi by killing fungal cells or spores or preventing their growth. Antifungal proteins (AFPs) produced by filamentous ascomycetes are ...

The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is ...

The ability to monitor the release in real-time provided valuable insights into the dynamics of the antifungal action. The characterization of the nanoparticles revealed a uniform size ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...