Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

IgG inhibition of a monoclonal antibody therapy can help with the selected deactivation of serum IgG with EndoS. Peptide glycosylation can be achieved using a two-step process involving EndoA or ...

Traditionally trained as an engineer, Aron received his PhD in chemical and biochemical engineering from Rutgers University in New Jersey, where he studied antibody glycosylation in the context of ...

The anti-TA-MUC1 is the antibody contained in DS-3939 ... MUC1 is a tumor-specific transmembrane glycoprotein with aberrant glycosylation due to changes of the expression patterns of some ...

Most individuals infected with HIV-1 develop neutralizing antibodies (Nab) capable of eliminating autologous ... and primarily involved changes in N-linked glycosylation. In addition, they showed that ...

From left, Florida State University faculty researcher Fanny C. Liu and Christian Bleiholder, a professor in the Department ...

Membrane proteins are key targets for therapeutic intervention using antibody biologics ... post-translational modifications, such as glycosylation, to function properly. Current technologies ...

One of the key areas of research is the N-glycosylation of monoclonal antibodies, which is a critical quality attribute affecting their efficacy and safety. A comprehensive review highlighted the ...

of the National Institute of Allergy and Infectious Diseases introduced multiple N-linked glycosylation sites to mask non-CD4bs regions of eOD-GT8 60mer to focus the antibody immune response to ...