Diagram of an antibody structure showing its key components ... region of an antibody houses the fragment crystallizable (Fc) region, which mediates interactions with Fc receptors expressed ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

ADS provides exceptional capabilities in antibody ... Fc regions. Optimized constant domains enable the rapid generation and idenitification of development candidates that retain critical ...