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Scientists uncover previously unknown target of alcohol in the brain: the TMEM132B-GABAA receptor complexThe researchers then used animal models to explore the role of TMEM132B. They generated genetically modified mice that either completely lacked the TMEM132B gene (knockout mice) or carried a ...
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Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibilityUsing advanced tools such as optogenetics, which uses light to control cells, the researchers uncovered that stimulating CINs in animal models of chronic alcohol exposure produced an altered ...
Rodent study identifies a brain circuit that is disrupted by alcohol exposure during prenatal development and contributes to poor decision-making in adulthood.
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