Figure 1: Imaging of amyloid-β deposits in the live mouse. Figure 3: In vivo imaging of amyloid-β deposits in 20-month-old homozygous PDAPP mice. Immunostaining with biotinylated or ...

Abnormal accumulation of the amyloid-β peptide (Aβ) in the brain appears crucial to pathogenesis in all forms of Alzheimer disease (AD), but the underlying mechanisms in the sporadic forms of AD ...

In related news, other scientists recently reported that phospho-tau isoforms in the CSF mirror protofibrillar forms of tau, ...

A study at Lund University reveals that traumatic brain injury alters the small vessels in the brain, resulting in an accumulation of amyloid beta—a hallmark of Alzheimer's disease. The findings ...

New research reveals how the combined impact of amyloid-β and tau deposits alters brain activity patterns in older adults, providing key insights into early Alzheimer’s disease progression.

Regular aerobic exercise was linked to a reduction in markers in the brains of in rats that associated with the onset of Alzheimer's, including amyloid plaques, according to a new paper in the ...

A collaborative research group has uncovered a new mechanism in the growth of amyloid β (Aβ) fibrils, which are closely associated with Alzheimer's disease. Using advanced high-speed atomic ...

Prolonged rapid eye movement sleep latency may be an early indicator of Alzheimer’s disease and related dementias, according ...