After diagnostic work-up had excluded a primary tumour elsewhere in the body, low grade astrocytoma or gliomatosis cerebri was considered and a stereotactic brain biopsy was performed ...

SNP318 is a brain-penetrating Lp-PLA2 inhibitor that ... deposits within cerebral vessels referred to as cerebral amyloid angiopathy (CAA). Finally, individuals with significant CAA, for example ...

Meta-analysis did not show a statistically significant difference in the levels of tau in the cerebrospinal fluid of people with cerebral amyloid angiopathy and people with Alzheimer's disease (effect ...

Histological examination shows amyloid-laden vessels and the appearance of Aβ in close association with inflammatory cells, implicating Aβ as the potential trigger for the inflammatory response.

Figure 1: Imaging of amyloid-β deposits in the live mouse. Figure 3: In vivo imaging of amyloid-β deposits in 20-month-old homozygous PDAPP mice. Immunostaining with biotinylated or ...

Microglia responses to amyloid beta can lead to inflammation, which in turn risks damage to brain tissues. The researchers wanted to know why immunotherapy turned microglia into ruthless cleaning ...

titled N-Acetylcysteine for hereditary cystatin C amyloid angiopathy (HCCAA), a nonrandomised clinical trial, details a new treatment approach for HCCAA, a rare and fatal genetic brain disorder ...

commonly called "hardening of the arteries," and beta blockers and vasodilators were associated with reduced odds of cerebral amyloid angiopathy, the buildup of a type of protein in brain blood ...

which is developing ALN-APP in collaboration with Regeneron for both Alzheimer’s and related condition cerebral amyloid angiopathy (CAA), which can cause haemorrhaging in the brain. Eisai and ...