Alpha-1 adrenergic receptors (α1-ARs) play a significant role in the regulation of cardiovascular function, particularly in conditions such as heart failure and myocardial infarction (MI).

Non-specific binding (other than to alpha receptors) to membrane prep or filter was quantified by identical procedure with the addition of 10 mM 1-norepinephrine to the incubation medium to occupy ...

CuraSen Therapeutics, Inc., a clinical-stage biopharmaceutical company developing oral, rapid onset, small molecule drugs to ...

"Interestingly, the receptor we identified as important in C. difficile infection [the alpha 2 adrenergic receptor] has also been linked to irritable bowel syndrome. I'm curious to know if there ...

The addition of β-adrenergic receptor antagonists to a medical regimen ... death due to heart failure of between 35% and 65% (Figure 1). This benefit has now been demonstrated for all classes ...

Epinephrine 0.15mg (1:2000); prefilled auto-injector; contains sulfites. Epinephrine acts on both alpha- and beta-adrenergic receptors. Through its action on alpha-adrenergic receptors ...

Third-generation α 1-adrenergic antagonists are pharmacologically uroselective in that they are competitive antagonists for prostatic α 1A-receptors. [16,17] Blockade of these receptors relaxes ...

Pressor effects by direct alpha-and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic stimulation ...