Spironolactone is commonly prescribed to lower blood pressure, and it may cause low ... other medications while taking spironolactone. That includes nutritional supplements (especially potassium ...
The landmark Randomized Aldactone Evaluation Study (RALES), published in 1999, showed that spironolactone, a potassium-sparing ... records of all prescription drugs dispensed and all ...
Similar increases in plasma aldosterone concentrations were also observed in the active treatment groups compared with those receiving placebo. Small increases in mean serum potassium levels were ...
Drugs that interfere with the ... but the average decrease after 1 year was greater in the spironolactone group (P = 0.004). Increases in serum potassium levels, however, were seen in ...