Scientists mapped fat tissue differences in obese individuals, uncovering cell changes linked to metabolic disease risk and ...

However, the increasing recognition that adipose tissue contains therapeutically useful cells, adipocytes suitable for gene therapy, with numerous advantages over other stem-cell sources ...

Body weight and body mass index alone are not enough to predict whether someone will develop a metabolic disease. A new atlas of cells in fat tissue could help to explain why some overweight people ...

Although obese individuals are at greater risk of diabetes, high blood pressure or high cholesterol, not all obese people ...

For the study, it was vital that the adipose tissue cells were not all simply lumped together, as this tissue comprises not only fat cells (adipocytes) but also cells of other types.

However, previous studies have mostly examined extracellular vesicles obtained from adipocytes and adipose tissue of mice.

And that is paradigm shifting.” While LCs looked like adipocytes, whole-tissue lipidomics performed on ear lipo-cartilage and groin adipose tissue revealed that the composition of the different fats ...

Recently, another type of cells called brown-in-white (BRITE) or beige cells, in white adipose tissue (WAT) have been found.3 BRITE cells possess a multilocular morphology, enriched mitochondria and ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

From that, the authors concluded that local hyperthermia could induce thermogenesis in humans by activating beige adipocytes. Roland Stimson, an endocrinologist at the University of Edinburgh in the ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.