Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia that is potentially curable with targeted therapies (such as all-trans retinoic acid and arsenic trioxide ...

RAPID-CRISPR test quickly and accurately diagnoses acute promyelocytic leukemia, a rare and aggressive blood cancer, with high sensitivity.

Chromosomal translocations of transcription factors generating fusion proteins with aberrant transcriptional activity are common in acute leukemia. In acute promyelocytic leukemia (APL), the ...

A new study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.

Shenderov survived the cancer. Now, as an associate professor and researcher at Johns Hopkins University, he helps others do the same. For Shenderov, the disease in the spotlight is acute ...

[Efficacy and Safety of the Induction Therapy with Different Doses of Anthracyclines for Patients with Newly Diagnosed Acute Promyelocytic Leukemia].

Researchers have identified a novel strategy for treating an aggressive form of leukemia – reprogramming the cancer cells to ...

However, we found that most acute myeloid leukemia (AML) cells, especially M4 and M5 subtypes, produce TNF and show basal level activation of RIP1/RIP3/MLKL signaling, yet do not undergo necroptosis.

Shenderov survived the cancer. Now, as an associate professor and researcher at Johns Hopkins University, he helps others do the same. For Shenderov, the disease in the spotlight is acute ...