Current guidelines recommend that children with acute pyelonephritis are initially treated with a parenteral third-generation cephalosporin such as ceftriaxone, and then oral antibiotics.

Montini G (2007) Antibiotic treatment for pyelonephritis in children: multicentre randomized controlled non-inferiority trial. BMJ 335: 386 Acute pyelonephritis is a serious disease, especially ...