This review evaluates GERD; dyspepsia; dyspepsia and ulceration induced by nonsteroidal anti-inflammatory drugs (NSAIDs), acetylsalicylic acid (ASA), or cyclo-oxygenase 2 (COX-2)-selective ...

A search for alternatives ensued, and in the late 1890s, Felix Hoffman of the Bayer Company in Germany found that acetylsalicylic ... COX-1 is involved in protecting the gastrointestinal tract ...

By inhibiting the COX pathway, aspirin diverts arachidonic ... Since then, aspirin, or acetylsalicylic acid (ASA), has remained one of the world's safest, least expensive, and most consumed ...

Aspirin, also known as acetylsalicylic acid (ASA), is a widely used medication ... Aspirin inhibits an enzyme known as cyclooxygenase (COX), which in turn reduces the production of thromboxane ...