Already known is that translational stalling upon amino acid starvation independently controls the elevated synthesis of the second messenger ppGpp through RelA, a protein intimately associated ...

Cells require ATP to power vital reactions. In the early phase of our planet's existence, however, the earth's atmosphere did not yet contain any oxygen. Nevertheless, studies of ancient bacteria ...

When bacteria come into contact with the film ... This disruption inhibits ATP synthesis and other essential biosynthetic processes, ultimately causing bacterial death due to DNA and membrane ...

TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. Resistance is achieved through mutations at position 63 or ...

Actin can also break down ATP, which causes the filaments to disassemble. These filaments have important functions in the outer membranes of cells, providing structural integrity as well as the ...