Challenging centuries-old assumptions about thermodynamics, a new study in published in Physical Review Letters has shown ...

acts as the motor domain of the molecule and pulls actin filaments along by repetitive conformational changes coupled to ATP hydrolysis. But to understand fully even this fundamental aspect of ...

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...

they injected ATP into ClC-3 protein samples before freezing to reduce hydrolysis. Researchers performed all-atom molecular ...