Deficiency of ADAMTS13 plays a critical role in platelet accumulation in PA-ILI, suggesting that ADAMTS13 could be a potential therapeutic target for this condition.

Low-molecular-weight heparin and recombinant a disintegrin and metalloproteinase with a thrombospondin type I motif member 13 (ADAMTS13) were applied. The necrotic liver area, hepatic platelet ...

Her condition improved following the introduction of glucocorticoids, plasma exchange, and rituximab, with a gradual return ...

TAK-755 is a recombinant version of the ADAMTS13 protein designed to replace the missing enzyme, which was given in the pivotal study as an intravenous infusion once every week or every other week.

医院供图 经过十余次线上线下多学科会诊，专家们一致认为，胎儿出生后可以通过注射“特效药”TAK-755来替代体内缺少的ADAMTS13酶，从而抑制血栓的 ...