Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

During translation, ribosomes can pause on the nucleic acid. Researchers showed that collisions from incoming proteins get ...

It is a beautiful piece of work. It provides a serious piece of heft to the hypothesis that specialized ribosomes not only exist but have important functional consequences in cellular processes.

My work benefited immensely from interactions with colleagues like Ada Yonath, who pioneered ribosome crystallography, and Thomas Steitz, who elucidated the large subunit’s structure.

We find that these inhibitors slow elongating ribosomes, thereby inducing a queue of pre-initiation complexes that can become positioned over and initiate from an otherwise poorly recognized start ...

"Ribosomes are very large macromolecular machines that very rapidly and precisely decode mRNA into protein. For a long time, they've been viewed as kind of 'dumb code-reading machines' that don't ...