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Nature Medicine | 从CAR-T到CAR-M:实体瘤免疫治疗的下一步革命
引言CAR-T(嵌合抗原受体T细胞)疗法在血液系统恶性肿瘤的治疗中取得了突破性进展。然而,由于实体瘤的肿瘤微环境(TME)高度免疫抑制、肿瘤抗原表达的异质性及T细胞渗透能力受限,CAR-T在实体瘤治疗中面临显著挑战。为克服这些问题,2月7日Natur ...
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